Cambridge core molecular biology biochemistry and structural biology fundamentals of inflammation edited by charles n serhan. Fundamentals of inflammation charles n serhan peter a ward derek w gilroy limited preview 2010 common terms and phrases a2a receptor activation acute adaptive immune adenosine receptor adhesion molecules afferent airway allergic animal models anti inflammatory antibodies antigen apoptosis arachidonic acid arthritis asthma autoimmune bacterial basophils binding blood bone cartilage cd4 . Fundamentals of inflammation serhan charles n phd ward peter a md gilroy derek w phd ayoub samir s the acute inflammatory response is the bodys first system of alarm signals that are directed toward containment and elimination of microbial invaders uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were . Fundamentals of inflammation april 2010 introduction the inflammatory response consists of an innate system of cellular and humoral responses following injury such as after heat or cold exposure ischemia reperfusion blunt trauma etc in which the body attempts to restore the tissue to its preinjury state