Focal therapy is a promising option for selected patients who have localized low or intermediate risk prostate cancer providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible numerous cohort studies have already investigated multiple focal techniques such as cryotherapy high intensity focused ultrasound brachytherapy photodynamic therapy laser therapy irreversible electroporation and . Over the last few years the concept of focal therapy for the treatment of prostate cancer pca has gained popularity and has been increasingly implemented in the field of localized pca treatment research various technologies have been proposed to target the treatment in specific zones of the prostate to avoid maximal local treatment particularly in cases with better prognosis thus low risk pca many efforts have been made to define the best indications for focal therapy but standard . Focal therapy is a promising option for selected patients who have localized low or intermediate risk prostate cancer providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible numerous cohort studies have already investigated multiple focal techniques such as cryotherapy high intensity focused ultrasound brachytherapy photodynamic therapy laser therapy irreversible electroporation and . Over the last few years the concept of focal therapy for the treatment of prostate cancer pca has gained popularity and has been increasingly implemented in the field of locali